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Drug ADME-associated protein database as a resource for facilitating pharmacogenomics research

Zheng, C. J., L. Z. Sun, L. Y. Han, Z. L. Ji, X. Chen and Y. Z. Chen (2004)."Drug ADME-associated protein database as a resource for facilitating pharmacogenomics research."Drug Development Research 62(2): 134-142.

Effect of molecular descriptor feature selection in support vector machine classification of pharmacokinetic and toxicological properties of chemical agents

Xue, Y., Z. R. Li, C. W. Yap, L. Z. Sun, X. Chen and Y. Z. Chen (2004). "Effect of molecular descriptor feature selection in support vector machine classification of pharmacokinetic and toxicological properties of chemical agents."Journal of Chemical Information and Computer Sciences 44(5): 1630-1638.

SVM-Prot: web-based support vector machine software for functional classification of a protein from its primary sequence

Cai, C. Z., L. Y. Han, Z. L. Ji, X. Chen and Y. Z. Chen (2003)."SVM-Prot: web-based support vector machine software for functional classification of a protein from its primary sequence." Nucleic Acids Research 31(13): 3692-3697.

Correlation between normal modes in the 20-200 cm(-1) frequency range and localized torsion motions related to certain collective motions in proteins

Cao, Z. W., X. Chen and Y. Z. Chen (2003)."Correlation between normal modes in the 20-200 cm(-1) frequency range and localized torsion motions related to certain collective motions in proteins."Journal of Molecular Graphics & Modelling 21(4): 309-319.

Can an in silico drug-target search method be used to probe potential mechanisms of medicinal plant ingredients?

X. Chen, C. Y. U., Y. Z. Chen (2003).Can an in silico drug-target search method be used to probe potential mechanisms of medicinal plant ingredients?” Natural Product Reports 20: 432-444


KDBI: Kinetic Data of Bio-molecular Interactions database

Ji, Z. L., X. Chen, C. J. Zhen, L. X. Yao, L. Y. Han, W. K. Yeo, P. C. Chung, H. S. Puy, Y. T. Tay, A. Muhammad and Y. Z. Chen (2003). "KDBI: Kinetic Data of Bio-molecular Interactions database."Nucleic Acids Research 31(1): 255-257.

Drug Adverse Reaction Target Database (DART) - Proteins related to adverse drug reactions

Ji, Z. L., L. Y. Han, C. W. Yap, L. Z. Sun, X. Chen and Y. Z. Chen (2003). "Drug Adverse Reaction Target Database (DART) - Proteins related to adverse drug reactions."Drug Safety 26(10): 685-690.

Internet resources for proteins associated with drug therapeutic effects, adverse reactions and ADME

Ji, Z. L., L. Z. Sun, X. Chen, C. J. Zheng, L. X. Yao, L. Y. Han, Z. W. Cao, J. F. Wang, W. K. Yeo, C. Z. Cai and Y. Z. Chen (2003). "Internet resources for proteins associated with drug therapeutic effects, adverse reactions and ADME."Drug Discovery Today 8(12): 526-529.